The topics for this course are typically allocated as follows (approximate number of lecture and lab hours spent on each topic are shown in the left columns):
Topic
Structure and bonding in organic molecules
Electronegativity, bond polarity, resonance structures, structural formulas (including Lewis structures, condensed structures, and line-angle structures), acids and bases, molecular orbitals, hybridization and geometry, isomerism, intermolecular forces, and thin layer chromatography.
Alkanes and cycloalkanes: Structure, nomenclature, physical properties, and conformational analysis.
Literature search.
Measurement of physical properties of organic molecules (melting point, boiling point, refractive index, density)
Spectroscopy: Theory and application of infrared and nuclear magnetic resonance spectroscopy and elements of unsaturation.
Gas Chromatography
Chemical Reactivity: equilibrium, enthalpy, entropy, kinetics, and mechanism.
Distillation: Macro- and micro-scale, simple, fractional, and steam.
Free-radical halogenation of alkanes.
Stereoisomers: Chirality, optical activity, absolute configuration and stereochemistry in chemical reactions
Alkyl halides: Structure, nomenclature, physical properties, reactions, and SN1, SN2, E1, and E2 mechanisms.
Extraction of natural products.
Alkenes: structure, nomenclature, physical properties, isomerism, synthesis, and reactions.
Sublimation.
Alkynes: structure, nomenclature, physical properties, acidity, synthesis, and reactions.
Alcohols: structure, nomenclature, physical properties, acidity, synthesis, and reactions.
Multi-step synthesis and recrystallization
Laboratory Practical and laboratory final exam
Final exam
Upon completion of this course, the student will be able to: